| ncRNA name | FASN siRNA |
| ncRNA Category | siRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RB cell lines WERI-RB1 and Y79 |
| Methods | siRNA transfection, qRT-PCR, Western blot, ELISA, microarray, MTT assay |
| Expression pattern | associated |
| Functional description | The differential phosphorylation status of the various PI3K/AKT pathway proteins (by western analysis) indicated that the FASN gene silencing indeed mediated apoptosis in RB cells through the PI3K/AKT pathway. Scratch assay clearly revealed that FASN silencing reduced the invading property of RB cancer cells. |
| PubMed ID | 25958981 |
| Year | 2015 |
| Title | Global gene deregulations in FASN silenced retinoblastoma cancer cells: molecular and clinico-pathological correlations. |
| Drug-related ncRNA | NO |
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